We present one of the top products of the project: the Handbook “Adaptive and close-to-nature management in mixed sub-humid Mediterranean forests: holm oak, chestnut, common oak and pine woods“. This guide presents the context, development, implementation and conclusions of MixForChange silviculture, a forest management model that incorporates climate change adaptive criteria with close-to-nature silviculture principles. We also present the practical lessons learned during the application and evaluation of this silviculture, and the opportunities and challenges for its large-scale adoption. The guide is especially aimed at practitioners and forest managers.